Dos Santos caught Velasquez with a punch to the ear that sent the champion stumbling to the canvas and followed up with unanswered punches on the ground that forced referee “Big” John McCarthy to stop the fight just over a minute into the scheduled five-rounder.
Dos Santos improves to 14-1 overall and 8-0 in the UFC following the win, while Velasquez falls to 9-1 after suffering his first loss.
In the UFC on Fox co-main event, lightweight contender Ben Henderson outpointed Clay Guida for a unanimous decision win to earn the next shot at champion Frankie Edgar.
The complete UFC on Fox results were:
- Junior dos Santos def. champion Cain Velasquez via TKO (punches) – Round 1, 1:04
UFC Heavyweight Championship
- Ben Henderson def. Clay Guida via unanimous decision (30-27, 29-28, 30-27)
- Dustin Poirier def. Pablo Garza via submission (D’arce choke) – Round 2, 1:32
- Ricardo Lamas def. Cub Swanson via submission (arm triangle) – Round 2, 2:16
- DaMarques Johnson def. Clay Harvison via TKO (punches) – Round 1, 1:34
- Darren Uyonyama def. Norifumi “Kid” Yamamoto via unanimous decision (30-27, 30-26, 30-27)
- Robert Peralta def. Mackens Semerzier via TKO (strikes) – Round 3, 1:54
- Alex Caceres def. Cole Escovedo via unanimous decision (30-27, 30-27, 30-27)
- Mike Pierce def. Paul Bradley via split decision (28-29, 30-27, 29-28)
- Aaron Rosa def. Matt Lucas via majority decision (28-28, 30-26, 30-26)
For complete post-fight UFC on Fox coverage stay tuned to MMAFrenzy.com.
Pictured: Junior dos Santos